Studies of Glycerol Transport Across the Rabbit Brush Border
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چکیده
منابع مشابه
Oxalate transport by anion exchange across rabbit ileal brush border.
This study demonstrates the presence of oxalate transporters on the brush border membrane of rabbit ileum. We found that an inside alkaline (pH = 8.5 inside, 6.5 outside) pH gradient stimulated [14C]oxalate uptake 10-fold at 1 min with a fourfold accumulation above equilibrated uptake at 5 min. 1 mM 4,4'-diisothiocyanostilbene-2,2'-disulfonate (disodium salt; DIDS) profoundly inhibited the pH-g...
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and plasminogen activator (Gordon et al., 1974). The synthetic pentapeptide Pz-peptide’ is also a substrate for macrophage enzyme(s) (C. H. Evans, D. C. Mears & J. L. Cosgrove, unpublished work). The neutral proteinases secreted by chondrocytes have, by comparison, received scant attention. Collagenase, ‘proteoglycanase’ and a non-specific proteinase that degrades globin have been reported (Des...
متن کاملDicarboxylic Amino Acid Influx across Brush Border of Rabbit Ileum
Glutamate and aspartate influxes across the brush border of rabbit intestine are saturable processes that are subject to competitive inhibition and are markedly influenced by the Na concentration in the mucosal solution. Lowering the Na concentration increases the amino acid concentration needed to elicit a half-maximal influx but does not significantly affect the maximal influx. The interactio...
متن کاملATP-driven copper transport across the intestinal brush border membrane.
The divalent metal ion transporter DMT1 is localized in the brush border membrane (BBM) of the upper small intestine and has been shown to be able to transport Mn2+, Fe2+, Co2+, Ni2+, and Cu2+. Belgrade rats have a glycine-to-arginine (G185R) mutation in DMT1, which affects its function. We investigated copper transport with BBM vesicles of Belgrade rats loaded with calcein, which exhibits fluo...
متن کاملEffect of hydrogen ion-gradient on carrier-mediated transport of glycylglycine across brush border membrane vesicles from rabbit small intestine.
Glycylglycine (Gly-Gly) transport across rabbit small intestinal brush border membrane vesicles was studied in the presence and absence of a Na+ gradient or a pH gradient. The transport was found to be entirely independent of Na+ but significantly stimulated by lowering extravesicular pH (pHo). The maximum stimulation was seen at pHo 5.5, where the uptake rate was about 2-times higher than the ...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1974
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(74)80137-x